The industry's own research.
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The October 2025 VTS Office Demand Index reports San Francisco became the top US office market with a VODI of 123, up 112 percent annually, versus New York at 78. Nationally, demand rose 16 percent year over year while declining 4 percent quarter over quarter.
The July 2025 VTS Office Demand Index reports a sharp divergence in second quarter office demand across major US markets, with some experiencing strong gains and others a steep deceleration.
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Life sciences venture capital funding reached 20.8 billion dollars in the first half of 2025, equal to 44.9 percent of the 2024 total. High rents in Boston-Cambridge, the Bay Area and San Diego pushed companies toward lower-cost markets.